Durbin has been an outspoken opponent of the process to confirm Kavanaugh, trying to push him in a high-wattage public hearing last week to endorse an FBI investigation into sexual assault allegations by Christine Blasey Ford.
Democrats paraded to a almost empty Senate chamber overnight and into Saturday to lambaste the nominee.
Republicans control the Senate by a 51-49 margin, and Saturday's vote seems destined to be almost party-line. Sen.
A final vote on Mr Kavanaugh's nomination could occur over the weekend. They reach a gentleperson's agreement to "pair" their votes if one of the senators will be absent.
Republicans can only lose a single GOP vote if all Democrats vote against the nomination.
One man yells 'you're a coward, Flake!' right before Jeff Flake votes yes. They raised concerns about his judicial philosophy and how he would rule on abortion and health care issues. Both he and Collins attempted to express a belief that Dr. Blasey Ford was assaulted, but not by Kavanaugh.
Millions of people watched as Ford testified before the Senate Judiciary Committee, describing a 1982 party where a drunk Kavanaugh and his friend, Mark Judge, allegedly pushed her into a room, pinned her down, groped her and covered her mouth when she tried to scream.
His promotion to the Supreme Court will also stand as a demoralizing defeat for Democrats who battled hard to block the 53-year-old judge at all costs. "Deborah Ramirez's lawyer said he was unaware of any corroborating witnesses who were interviewed".
If he wins confirmation, Kavanaugh - who has faced a bruising process that raised questions over his candor, partisan rhetoric, and his lifestyle as a young man - will seal a conservative majority on the nine-seat high court, possibly for decades to come.
Meanwhile, Republicans raged against the other women's accusations.
Collins, who also voted yes on cloture, informed reporters of her plans minutes beforehand.
"Republicans are saying: your voices just don't matter", Sen.
The Senate is expected to vote Saturday on the Supreme Court nomination of Judge Brett Kavanaugh and - barring a major unforeseen development - in all likelihood, he will be confirmed by the narrowest of margins.
The Senate is set to take a procedural vote at 10:30 a.m., ET Friday to end debate on the nomination.
"It's been a great political gift for us".
Manchin expressed empathy for sexual assault victims.
Sen. Dianne Feinstein: "The most notable part of this report is what's not in it".
Trump stood by Kavanaugh, a federal appeals court judge with a history of advancing Republican causes, and this week mocked Ford's account of what she says was a drunken attack on her by Kavanaugh when they were teenagers. To deny she knows her attacker is to deny her entire story. "The Me Too movement is real, it matters, it is needed, and it is long overdue".