During her tour on Wednesday, Melania Trump walked slowly with a guide through various wings, asking questions.
She adds that the castle is a "special place".
Trump arrived in Ghana on Tuesday wearing a Manolo Blahnik court shoes and a red and white striped dress by French fashion house Céline, as she was greeted by Ghana's own First Lady, Rebecca Akufo-Addo.
Trump's tour of Africa may well be meant to help heal some wounds caused by her husband, who once reportedly referred to Haiti and some African nations as "shitholes" during a meeting on immigration back in January.
First lady Melania Trump's communications director, Stephanie Grisham, and her chief of staff, Lindsay Reynolds, are traveling with her.
Some, including The Washington Post's Adam Taylor, have suggested that the First Lady's trip is simply her attempt to boost the image of the Trump presidency across the continent (spoiler: The Donald said some not great things about Africa and it's people), but even if that's true, it's good to see that Melania is showing reverence and respect where it's due. The two first met last week in NY at a reception on the sidelines of the U.N. General Assembly, where Mrs. Trump spoke about her upcoming trip. She passed a row of cannons and descended into a dungeon where male slaves were held in chains.
She was also seen wearing a pair of her favorite Manolo Blahnik heels first thing in the morning - however she changed out of the sky high pumps and into the low-cost flats by the time she reached the 17th Century castle, no doubt in order to ensure she could enjoy the walking tour without worrying about her feet.
"Did you say President Trump's wife just arrived in Accra?" street vendor Awo Yeboah asked.
The first lady's visit was a lower-key affair than Obama's visit as the first black USA president, and reminders of his visit with wife Michelle were prominent.
The former model, whose choice of clothing is keenly watched, changed from a safari-inspired departure outfit of suede trench coat and leopard print heels to a red and white striped dress with white pumps by the time she arrived in West Africa.The 48-year-old is promoting her Be Best initiative, her official agenda unveiled in May created to improve children's well-being.
But unlike her predecessors, Melania Trump's tour will be followed closely to see if she can build bridges after her husband's apparent disparaging comments.
She then donned it again the following day before going to visit a local children's hospital, where she spent time meeting some of the patients. Her five-day, four-nation tour will also include stops in Malawi, Kenya and Egypt.