Juventus B won the first game 3-2 but they have not beaten the first team in the match since 2005.
Ronaldo started the match and marked the occasion with a goal before an own goal and a quick fire brace from Paulo Dybala gave Juventus a commandable lead heading into the break.
Cesare Bertoncello, from Turin, who was pointed out to AFP by security as being the first person to arrive in the queue to get into the ground at 0900 (0700 GMT) recalled the dominating presence of the Agnellis in years passed.
Massimo Savelli from near Siena, some 450 kilometres to the south east, got up at 0600 to be in Villar Perosa for the first time in decades of supporting his team.
Ronaldo proved good value for the hype, scoring in the 10th minute with a neat finish after breaking a loose offside trap and closing in on goal completely unmarked. When you play the Champions League quarter-finals against Juventus, you can see signs and the whole stadium applauds you, it's incredible!
The five-time Ballon d'Or victor didn't waste much time getting into the good graces of his new supporters, as he found the net just eight minutes into his Juventus debut in a 3-2 friendly defeat by Juventus B.
You can't help but be excited at Ronaldo's arrival in the Italian capital.
Juve made it 5-0 early in the second half through Claudio Marchisio, before the traditional pitch invasion brought the game to a close in the 70th minute. Ronaldo tries to keep the ball up for his teammate but mis-controls the ball leaving him red-faced and his opponents in stitches.
Juventus kick off the defence of their Serie A title against Chievo on Saturday.
Ronaldo, who joined the Serie A champions last month in a deal worth a £100million, made the ideal start to life in Turin.