"We can't defeat the nominee on our own", said a Democratic senator who requested anonymity to discuss internal party deliberations. Businessman Jeff Greene, a newcomer to the race who unsuccessfully sought the nomination in 2010, took it a step further.
The reaction of her constituents in ME to Kavanaugh's nomination has been "very mixed", she said. The chief justice earned a 2018 equivalent of about $254,000.
Alan Schroeder, journalism professor at Northeastern University in Boston, said that "one of the peculiarities of the Trump presidency is that everything this White House touches gets turned into a spectacle, intentionally or not".
Speaking to Al Jazeera, Nihad Awad, the national executive director of the Council on American-Islamic Relations (CAIR) said that the Senate must grill Kavanaugh on his views on civil rights and presidential powers.
Kavanaugh spent 12 years as a judge on the US Court of Appeals in Washington, DC, and has a record of more conservative rulings on environmental cases, favoring industry over regulators especially in cases related to greenhouse gas emissions.
Another issue the opposition will press him on is whether he would maintain Roe v. Wade, which as a judge, he shouldn't have to comment on.
"Congress might consider a law exempting a President-while in office-from criminal prosecution and investigation, including from questioning by criminal prosecutors or defense counsel", he wrote. He supported releasing the girl to a sponsor, where she could obtain an abortion if she chose to do so and leave the government out of it.
Experts said that Kavanaugh's dissent was really "somewhat" of a middle-ground approach.
One case likely to draw attention is Kavanaugh's 2015 dissenting opinion on the health care law's contraceptives mandate.
Senate Democrats admitted it will be hard to defeat Kavanaugh with only 49 seats in their caucus, but their goal is to inflict as much political damage on the GOP as possible ahead of the November midterm elections.
Mr Trump called it an "honour and privilege" to nominate Judge Kavanaugh, who became a judge for the US Court of Appeals in 2006, and said he had "impeccable credentials and unsurpassed qualifications".
That said, the dissent does give some clues about Kavanaugh's stance. He's also sided with abortion opponents. And Kavanaugh has ruled in ways that affirm the Trump administration's racist immigration policy.
A product of the Republican legal establishment in Washington, Kavanaugh is a former law clerk for retiring Justice Anthony Kennedy. "He emphasized in his remarks that he respects precedent, but every nominee says that".
"With a Justice Kavanaugh on the Supreme Court, we could see reversals of hard-won gains securing equal opportunity in education, employment and housing", the National Association for the Advancement of Colored People (NAACP) said in a statement.
"An "operative" makes it sound like someone who just sort of didn't care what the facts were and was only interested in painting it in its most unflattering" light, Leipold said.
Sen. Chuck Grassley (R-Iowa), told CNN on Wednesday that he estimates that confirmation hearings for Brett Kavanaugh to the Supreme Court would be at least by early September.