Forecasters have called Winter Storm "Grayson" a "bomb cyclone", as its steep drop in pressure helped create winds gusting at as high as 50 miles per hour.
An American Airlines spokesman says the airline plans to cancel all flights scheduled for Thursday at Boston Logan International Airport because of the forecast calling for snow and high winds.
More than 3,000 flights have been cancelled within the US, as of Thursday morning, according to flight tracking website FlightAware. Boston weather was anticipated to be particularly severe, with up to 18 inches of snow predicted, according to the National Weather Service.
At Newark Liberty airport in New Jersey, airlines had cancelled 867 flights as of noon Thursday, 73 percent of normal flight activity.
The snowstorm sweeping up the East Coast is ruining travel plans for many, with thousands of USA flights canceled.
A total of 12 flights had been canceled departing and arriving from Portland International Airport, mainly from NY and Boston.
In Washington D.C., the federal government delayed opening offices on Thursday as blowing snow swirled in the capital. Meanwhile, more than 12,400 Georgia Power customers, 10,200 Florida Power & Light customers and 2,700 South Carolina Electric & Gas customers have been affected since Wednesday night, local media reported.
Blizzard warnings and winter storm warnings have been issued along the Atlantic coast from Virginia Beach to Maine.
Southern cities were not immune from the winter storm. No injuries were reported.