He identified himself to CNN as Jake Byrd, the stage name of a comedian known for interrupting news events as part of the "Jimmy Kimmel Live!"
"When I say they who are 'they?'" he asked rhetorically.
He insists that the allegations claiming he initiated a sexual encounter with a 14-year-old girl when he was 32 are untrue and he denies the stories of several other women who went public with their experiences with him when they were also teens.
Moore was not amused by the disruption and took to Twitter to demand that if Kimmel wants to "mock our Christian values" he should "come down here to Alabama and do it man to man".
"Sounds great Roy - let me know when you get some Christian values and I'll be there!"
Moore responded with an invitation.
The fight began after the TV host sent a correspondent to one of the candidate's rallies in Alabama
President Donald Trump will not be campaigning for accused child molester Roy Moore, but he will hold a campaign rally just four days before the December 12 special election. "P.S. - wear that cute little leather vest".
Moore is now firing back. "You cannot have a Doug Jones [Moore's Democratic opponent] up there who's an extreme liberal Democrat doing all he can to deny Donald Trump his nominee on the Supreme Court".
Moore began his remarks by blaming liberals for the country's political woes.
On Wednesday, Moore doubled down on proclaiming his innocence. "They've tried unsuccessfully to change that". They are socialists who want to change our way of life.
The women accuse Moore of making several unwanted phone calls in an attempt to solicit a romantic relationship, as well as inappropriately touching and kissing them. He cited a report from a rightwing news network.
The Alabama Republican now has a narrow poll lead against Jones in the special election for the Senate seat vacated by Jeff Sessions' appointment as USA attorney general.