"While everyone is entitled to their own opinions, I don't think it's too much to ask National Football League players to respect the flag", Mr Pence added.
"I left today's Colts game because President Trump and I will not dignify any event that disrespects our soldiers, our flag, or our national anthem".
The Republican had posted a picture of himself ahead of Sunday's game, stating he was there to honor the career of former quarterback Peyton Manning, whose No. 18 jersey is being retired by the Indianapolis Colts. According to Trump, it was his idea.
He said in a tweet on Sunday that he asked Pence to leave the stadium "if any player kneeled, disrespecting our country". Jason La Canfora of CBS said that he was relying on previous reporting about the anthem when he said in a televised report that Kaepernick said he would stand if he played in the National Football League again.
"He's not planning on kneeling.and he's planning on standing for the anthem", La Canfora said. He said he was proud of Pence and his wife, Karen. He was merely relaying what had already been reported about Kaepernick in other outlets, La Canfora wrote, adding, "what he would do during the Anthem I do not know".
The protests started when Colin Kaepernick sat down for the anthem before a game in August 2016. "He has never discussed this with anyone". He wanted to protest against the repression of which were victims of Blacks in the United States.
Last week approximately 30 players from the 49ers kneeled in their first game since Trump called for players who protest to be fired.
Pence, who has gone out of his way to demonstrate loyalty to Trump, said in his statement it was important to rally around the flag and things that unite the country.
The vice president went on to issue a full statement opposing the protest. After having players kneel last week, both the Detroit Lions and Buffalo Bills all stood for the anthem before their games.